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Prader-Willi Syndrome
The Genetics
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Chromosome – a strand of DNA.

Gametogenesis – the production of gametes, which is a special cell which fuses with another gametes during fertilization in sexually reproduction organisms.

Imprinting Centre - controls the imprinting of the genes in the imprinted region

Imprinted Region - a region which is expressed by only either the maternally or paternally contributed chromosome whilst the other one remains inactive.

Meiosis – cell division found in sexually reproduction organisms in which the number of chromosomes in the daughter cells goes from diploid (a pair of each chromosome) to haploid (only one of each chromosome).

Nondisjunction – the failure of chromosomes to correctly separate during cell division leading to an abnormal number of chromosomes in the daughter cells.

Phenotype – the physical appearance of an organism.

Trisomy – three copies of the chromosome are present, instead of the normal two.

 
 
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© Sally Price 2007  Leeds